Aging and Neurotransmitter Systems

  • P. L. McGeer
  • E. G. McGeer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 113)


The aging process is accompanied by substantial alterations in physiological function. Decreased total motor activity, declin- ing mental acuity and altered endocrine performance are among the obvious changes that take place. Within the brain, lipofuscin deposits accumulate and the total weight tends to shrink.


Tyrosine Hydroxylase Substantia Nigra Locus Coeruleus AChE Activity Neurotransmitter System 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • P. L. McGeer
    • 1
  • E. G. McGeer
    • 1
  1. 1.Kinsmen Laboratory of Neurological Research, Department of PsychiatryUniversity of British ColumbiaVancouverCanada

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