Oxygen Diffusion, Conductivity and Solubility Coefficients in the Microarea of the Brain

Measurements with Noble Metal Microelectrodes
  • D. K. Clark
  • W. Erdmann
  • J. H. Halsey
  • E. Strong
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 92)


Oxygen transport to the cells occurs in three major steps: Oxygen uptake in the lungs, oxygen transport via the blood and oxygen diffusion from blood to tissue. So far, oxygen diffusion in tissue could only be determined indirectly by using slices of tissue on thin layers of medium taken out of their context. It had been assumed that these tissues had the same characteristics for oxygen diffusion as normal tissue. It had not been taken into account that the diffusion coefficient of oxygen very much depends on the constitution of the medium, the protein concentration, the size of intercellular space and the density of cellular net work.


White Matter Oxygen Diffusion Oxygen Transport Mongolian Gerbil Solubility Coefficient 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • D. K. Clark
    • 1
  • W. Erdmann
    • 1
  • J. H. Halsey
    • 1
  • E. Strong
    • 1
  1. 1.Departments of Anesthesiology and NeurologyUniversity of Alabama in BirminghamBirminghamUSA

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