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Oxygen Supply to the Cirrhotic Liver Following Various Portacaval Shunt Proceudres

  • Ch. Broelsch
  • J. Höper
  • M. Kessler
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 92)

Abstract

Hemodynamic measurements have been of limited value in determining the stage of liver cirrhosis and the type of · portacaval shunt to be performed in the presence of portal hypertension and bleeding esophageal varices (Bradley et al. 1953, Reynolds, 1974). The effective perfusion rate and oxygen transport to the tissue, required to sustain regenerative and functional capacity of the residual hepatocytes cannot be detected by determination of intraoperatively obtained hemodynamic parameters such as portal venous flow and pressure, wedged hepatic pressure and hepatic arterial flow because of the various compartments of intrahepatic blood circulation, the severely altered liver anatomy and an unknown portion of the hepatic inflow which is routed through func-tionless intrahepatic anastomoses (Price et al.1967). The necessity of portal venous decompression requires the shunting of the nutritional and oxygen enriched portal blood into the systemic circulation, leaving the cirrhotic liver with an arterial inflow through the hepatic artery only.

Keywords

Cirrhotic Liver Portal Blood Portacaval Shunt Portal Venous Flow Portal Venous Blood 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Ch. Broelsch
    • 1
    • 2
  • J. Höper
    • 1
    • 2
  • M. Kessler
    • 1
    • 2
  1. 1.Klinik für Abdominal- und TransplantationschirurgieHannoverGermany
  2. 2.Medizinische HochschuleMax-Planck-Institut fuer SystemphysiologieDortmundGermany

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