How to Quantify Skeletal Muscle Capillarity
The capillarity in skeletal muscle is not adequately defined by either capillary density or by capillary to fiber ratio. Capillary density gives no clue as to the evenness of the distribution of the capillaries in muscle cross sections but the reciprocal of capillary density provides an estimate of the area of tissue cross section served by the average capillary, a value used by Krogh and other investigators (Tenney, 1974). The capillary to fiber ratio renders no information on the area of tissue served by each capillary. Further, capillary density and C/F give no indication of the maximal diffusion path length, important in assessing the capacity of muscle for oxygenation. For these reasons, we have been interested in finding a better method of obtaining data that could be used to estimate diffusion distances. This paper describes capillarity in skeletal muscle using several methods of quantification that, we believe, provide a better understanding of the transport of oxygen within the muscle.
KeywordsMuscle Tissue Diffusion Distance Capillary Density Fiber Size Large Fiber
Unable to display preview. Download preview PDF.
- Akmal, K., Bruley, D.F., Banchero, N., Artigue, R. and Maloney, W. (1977) Plenum Press.Google Scholar
- Elias, H., Hennig, A. and Schwartz, D.E. (1971) Physiol. Rev. 51, 1958.Google Scholar
- Sillau, A.H. (1977) Ph.D. Thesis. Colorado State University, Fort Collins, Colorado.Google Scholar
- Sillau, A.H. and Banchero, N. (1977) Proc. Soc. Expt. Biol. Med. 154, 461.Google Scholar
- Sillau, A.H. and Banchero, N. (1977a) Pflügers Arch. (in press).Google Scholar