Oxygen Transport Impairment Induced by Three Major Cardiovascular Risk Factors
This paper is a report on examinations of the oxygen affinity of hemoglobin in subjects with diabetes mellitus, with hyperlipoproteinemia and in smokers, indicating the presence of a fluctuating disorder in the oxygen unloading from the erythrocytes in these conditions known as cardiovascular risk factors. Since these states may also be associated with an impairment in microcirculatory flow, the synergistic effects of these factors may lead to serious consequences for the oxygenation of tissues, particularly in those with a poor microcirculation as in the arterial walls.
KeywordsOxygen Transport Diabetic Child Oxygen Affinity Arterial Smooth Muscle Cell Lipid Degradation
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- Asano, M. and Brånemark, P.-J. (1970) In ‘Advances in Microcirculation’ p.125 (ed. Härders, H.) S. Karger, Basel, New York.Google Scholar
- Ditzel, J. (1962) The conjuctival vessels in diabetes mellitus. Scand. Univ. Books, Munksgaard, Copenhagen.Google Scholar
- Ditzel, J. (1975) In ‘The Eye and Systemic Disease’ p. 179, (ed. Mausolf, I.A.) C.V. Mosby Co., St. Louis.Google Scholar
- Ditzel, J. (1976a) In ‘Microcirculation 2. Transport Mechanisms Disease States’ p. 88 (eds. Grayson, J. and Zingg, W.). Plenum Press, New York.Google Scholar
- Ditzel, J. and Dyerberg, J. (1977a) Metabolism 25, 14.Google Scholar
- Kroeger, A. (1970) In ‘Advances in Microcirculation’ p.1 (ed. Harders, H.). S. Karger, Basel, New York.Google Scholar
- Robertson, A.L. Jr. (1968) Progr. Biochem. Pharmacol. 4, 305.Google Scholar
- Ross, R. and Glomset, J.A. (1976) New Engl. J. Med. 295, 269.Google Scholar
- Wissler, R.W. (1974) In ‘The myocardium: Failure and Infarction’ p. 155 (ed. Braunwald, W.). H.P. Publishing Co., New York.Google Scholar