Oxygen Transport Impairment Induced by Three Major Cardiovascular Risk Factors

  • Jørn Ditzel
  • Per Jæger
  • Jørn Dyerberg
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 92)


This paper is a report on examinations of the oxygen affinity of hemoglobin in subjects with diabetes mellitus, with hyperlipoproteinemia and in smokers, indicating the presence of a fluctuating disorder in the oxygen unloading from the erythrocytes in these conditions known as cardiovascular risk factors. Since these states may also be associated with an impairment in microcirculatory flow, the synergistic effects of these factors may lead to serious consequences for the oxygenation of tissues, particularly in those with a poor microcirculation as in the arterial walls.


Oxygen Transport Diabetic Child Oxygen Affinity Arterial Smooth Muscle Cell Lipid Degradation 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Jørn Ditzel
    • 1
  • Per Jæger
    • 1
  • Jørn Dyerberg
    • 1
  1. 1.Department of Medicine and Clinical ChemistryAalborg Regional HospitalDenmark

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