Gas Transfer through the Skin: A Two-Layer Model Relating Transcutaneous Flux to Arterial Tension
Recent developments in clinical application of transcutaneous blood-gas sensors show promise for continuous, noninvasive monitoring of arterial oxygen and carbon dioxide tensions (Huch et al., 1975). In practice, a probe placed in contact with the skin is used to measure the flux of gas between the skin and the gas space within the probe. The probe or skin electrode is calibrated to relate measured gas flux to arterial tension. Since the flux through the skin depends on many variables an accurate correlation between measured flux and blood-gas tension requires a basic understanding of the overall skin permeation process.
KeywordsMass Transfer Coefficient Lower Abdomen Effective Permeability Carbon Dioxide Tension Arterial Tension
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