Calculation of the Facilitation of O2 or Co Transport by HB or MB by Means of a New Method for Solving the Carrier-Diffusion Problem

  • L. Hoofd
  • F. Kreuzer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 92)


A new analytical approximation is used for calculating facilitated diffusion in flat layers. It is applied to oxygen or carbon monoxide diffusion through flat layers containing myoglobin or hemoglobin, where it can be applied to all situations. Calculations for the total gas flux are in good agreement with data from the literature. New calculations for the facilitated diffusion of CO show non-equilibrium facilitation over a wide range of layer thicknesses and CO pressures.


Layer Thickness Break Line Analytical Approximation Damkohler Number Total Substrate 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • L. Hoofd
    • 1
  • F. Kreuzer
    • 1
  1. 1.Department of PhysiologyUniversity of NijmegenNijmegenThe Netherlands

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