Multi-Capillary Model for Oxygen Transport to Skeletal Muscle
Systems of nonlinear, unsteady-state, partial differential equations have been developed to model oxygen transport in the microcirculation of brain using the Krogh cylinder as the basic anatomical unit (Reneau, Bruley and Knisely, 1967). The models have been solved to predict trends in behavior but it has been impossible to test them against accurate in-vivo quantitative data from brain because of the experimental difficulties in determining the exact position of PO2 eletrodes in the capillary-neuron network. Because of this we have tried to find an animal model that would reduce the histological complexity of the system and allow us to test the validity of the mathematical models.
KeywordsOxygen Transport Equilateral Triangle Axial Diffusion Capillary Radius Radial Point
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