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Mechanisms of Action for Somatotropin in Growth

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Abstract

Physiological processes such as growth are carefully orchestrated and controlled by complex interactions among a multiplicity of hormones (Bell et al., 1987). Somatotropin (ST) is a key somatotropic hormone and homeorhetic control. It exhibits regulatory effects on metabolism and consequently affords control over how absorbed nutrients are partitioned for growth and lactation. ST plays a pivotal role in metabolism not only during nutrient adequacy, but also during periods where nutrients are severely deficient or poorly utilized (e.g., starvation, diabetes). The metabolic and endocrine “axis” for determining how ST effects are manifested, in the two extremes cited, is the subject of an excellent review by Phillips (1986). This chapter assumes relative nutrient adequacy, commensurate with the needs for normal growth in farm animals.

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Boyd, R.D., Bauman, D.E. (1989). Mechanisms of Action for Somatotropin in Growth. In: Campion, D.R., Hausman, G.J., Martin, R.J. (eds) Animal Growth Regulation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8872-2_12

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