Use of Washed Sperm for Removal of Sperm Antibodies
Certain men and certain women develop sperm antibody activity, and this can be demonstrated in the blood serum; in many cases, this activity can also be shown in the genital secretion. The presence of such antibody is generally associated with a reduction in that person’s fertility.1-5 Hence, it is now considered that, among the various mechanisms that may operate in problems of spontaneous infertility, we can separate a group of patients who are said to have “immune infertility”.3 This antibody activity is usually detected and evaluated by methods of sperm agglutination or immobilization.6,7 These methods can be adjusted in specificity and sensitivity so that they reflect quite well the clinical relevance of the infertile or the fertile condition.
KeywordsSperm Cell Infertile Couple Cervical Mucus Basal Body Temperature Antisperm Antibody
Unable to display preview. Download preview PDF.
- 2.Shulman, S. Sperm antibodies as a cause of problems in infertility and in vasectomy. In: Immunology in Obstetrics and Gynaecology, Proceedings of the First International CongressPadua, 1973. Eds. A centaro and N. Caretti, Excerpta Medica, Amsterdam, p. 41, 1974.Google Scholar
- 3.Shulman, S. Reproduction and antibody response. CRC Press, Cleveland, 1975.Google Scholar
- 5.Behrman, S.J. The immune response and infertility. In: Pro gress in Infertility, 2nd ed., Eds S.J. Behrman and R.J. Kistner, Little Brown, Boston, p. 793, 1975.Google Scholar
- 6.Rose, N.R., Hjort, T., Rümke, P., Harper, M.J.K. and Vyazov, O. Techniques for detection of iso and auto-antibodies to human spermatozoa. Clin. Exp. Immuno1., 23:175, 1976.Google Scholar
- 7.Shulman, S. Human sperm antibodies and their detection. In: Manual of Clinical Immunology, Eds. N.R. Rose and H. Friedman Chap. 95, Waverly Press, Baltimore, p. 710, 1976.Google Scholar