Biochemical Modifications of Frozen Semen

  • Jean-François Guerin
  • Yves Menezo
  • Jean-Claude Czyba


The preservation of human semen in liquid nitrogen is now a common practice which has permitted a considerable extension in the application of artificial insemination, and whose advantages are now well proven. However, there is one major problem with the cryo- preservation of human semen: The incontestable drop in fertilizing capacity. Several authors have correlated this with the reduction in motility of a sample after thawing which is, indeed, more marked for human semen than for the majority of domesticated species(especially cattle). It would, however, seem clear that post-thaw motility is not a sufficient criterion of fertilizing power of a frozen semen sample. According to Behrman “The post thaw motility of a frozen preserved semen is not a determinant or index of its subsequent fertility” .3 In addition, certain frozen semen samples appear to loose all their fertility capacity even though residual motility is good.


Seminal Plasma Artificial Insemination Human Spermatozoon Deep Freezing Residual Motility 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Jean-François Guerin
    • 1
  • Yves Menezo
    • 1
  • Jean-Claude Czyba
    • 1
  1. 1.Centre d’Etudes et de Conservation du Sperme (CECOS), LyonLyonFrance

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