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Acoustic Priming of Audiogenic Seizures in Mice

  • Kenneth R. Henry
  • Robert E. Bowman

Abstract

The audiogenic seizure is a classic example of an extra-auditory physiological effect of audible sound. This distinctive behavior has been studied in animals in the hope that knowledge of its mechanism might aid in the understanding of both sensory-induced and spontaneous seizures in man. Recently, it has been discovered that prior intense auditory stimulation can induce or enhance susceptibility to audiogenic seizures in mice. This “acoustic priming” effect represents a new phenomenon which may be useful in seizure research, especially if a similar effect is observed in man. This chapter describes a series of on-going experiments which have been designed to examine the priming effect.

Keywords

Inbred Mouse Temporal Summation Retrograde Amnesia Sensitive Period Electroconvulsive Shock 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • Kenneth R. Henry
    • 1
  • Robert E. Bowman
    • 1
  1. 1.Regional Primate Research CenterUniversity of WisconsinMadisonUSA

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