The Aspergilli as Pathogens of Cultured Fishes

  • Benjamin E. Olufemi


The genus of moulds known as Aspergillus has always been a factor in man’s environment. Even before the development of the microscope, Aspergillus colonies were well known as the white, yellow, green, red or black moulds seen on foods and rotting vegetation, although of course attempts at proper interpretation of the cause of such growths were not feasible.


Rainbow Trout Aspergillus Species Coho Salmon Otitis Externa Cladosporium Cladosporioides 
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  1. Alderman, D.J. (1982) Fungal disease of aquatic animals, in R.J. Roberts (ed.), Microbial Diseases of Fish, Special Publications of the Society for General Microbiology. No. 9, Academic Press, London and New York, pp. 189–242Google Scholar
  2. Allcroft, R. and Carnaghan, R.B.A. (1963) Toxic products in ground-nuts; Biological effects. Chem. Ind. (London), 2, pp. 50–3Google Scholar
  3. Ashley, L.M., Halver, J.E. and Wogan, G.N. (1964) Hepatoma and aflatoxicosis in trout. Fed. Proc, 23, p. 105Google Scholar
  4. Ashley, L.M. (1970) Pathology of fish fed anatoxins and other antimetabolites, in S.F. Snieszko (ed.), A Symposium on Diseases of Fishes and Shellfishes, American Fisheries Society, New York, pp. 366–79Google Scholar
  5. Austwick, P.K.C. (1965) Pathogenicity, in K.B. Raper and D.I. Fennel (eds.) The Genus Aspergillus, Williams and Wilkins Co, Baltimore, pp. 82–126Google Scholar
  6. Bary, A.De. (1854) Ueber die ent Wickelung und den Zusammenhang von Aspergillus glaucus und Erotium. Botan. Ztg., 12, pp.425–34; 441–51; 465–71Google Scholar
  7. Bothast, R.J. and Fennel, D.I. (1974) A medium for rapid identification and enumeration of A. flavus and related organisms. Mycologia, 66, pp.365–9CrossRefGoogle Scholar
  8. Butler, W.H. (1965) Liver injury and aflatoxin in G.N. Wogan (ed.) Mycotoxins and Foodstuffs, MIT Press, Cambridge, Mass.Google Scholar
  9. Campbell, A.D. (1972) Chemical and biological alterations of mycotoxins and their relationship to control of the mycotoxin problem. Abstracts, IUP AC Symposium. Control of Mycotoxins, Göteborg, Sweden, p. 6Google Scholar
  10. Carmichael, J.W. (1966) Cerebral mycetomata of trout due to a phialophora-like fungus. Sabouraudia, 5, pp. 120–3CrossRefGoogle Scholar
  11. Coates, J.A., Potts, T.J. and Wilcke, H.L. (1967) Interim hepatoma research report. Trout Hepatoma Research Conference Papers. US Fish and Wildl. Serv., Res. Rep. 70, pp. 34–8Google Scholar
  12. Cramer, C. (1859) Ueber eine neue fadenpilzgattung, Sterigmatocystis. Viertel Jahresschrift Naturforsch. Ges., Zurich, 4, pp. 325–37Google Scholar
  13. Dollear, F.G. (1969) Detoxification of aflotoxins in foods and feeds, in L.A. Goldblatt (ed.) Aflatoxins, Academic Press, New YorkGoogle Scholar
  14. Eggins, H.O.W. and Coursey, D.G. (1968) The industrial significance of the biodeterioration of oilseeds. Int. Biodetn Bull., 4, p. 29Google Scholar
  15. Eveland, W.C. Marshall, J.D. and Silverstein, A.M. (1957) Specific immunochemical staining of Cryptococcus neoformans. Am. J. Pathol., 33, pp. 616–17Google Scholar
  16. Fijan, N. (1969) Systemic mycosis in channel catfish. Bull. Wild. Dis. Assoc, 5, pp. 109–10Google Scholar
  17. Fischer, E. (1897) Plectascineae, in A. Engler and K. Prautl (eds.) Die Naturlichen Pflanzenfamilien, Teil 1, Abt. 1. Wilhelm Engelmann, Leipzig, pp. 290–320Google Scholar
  18. Forgacs, J. (1962) Mycotoxicoses in animal and human health. Proc US Livestock Sanitary Assoc., 66th Ann. Meeting, 1962, pp. 426–48Google Scholar
  19. Forgacs, J. and Carll, W.T. (1962) Mycotoxicoses. Adv. Vet. Sci., 7, pp. 273–382Google Scholar
  20. Goldblatt, L.A. (1973) Learning to live with mycotoxins: Aflatoxin — a case history. Pure Appl. Chem., 35, p. 223CrossRefGoogle Scholar
  21. Halver, J.E. (1965) Aflatoxicosis and rainbow trout hepatoma, in G.N. Wogan (ed.), Mycotoxins in Foodstuffs, MIT Press, Cambridge, Mass., pp. 209–34Google Scholar
  22. Halver, J.E. (1967) Crystalline aflatoxin and other vectors for trout hepatoma, in J.E. Halver and I.A. Mitchell (eds.). Trout Hepatoma Research Conference Papers, Res. Rep. 70, BSFW, GPO, Washington DC, pp. 78–102Google Scholar
  23. Halver, J.E. (1969) Aflatoxicoses and trout hepatoma, in L.A. Goldblatt (ed.), Aflatoxins, Academic Press, New York, pp. 265–306Google Scholar
  24. Harrison, J. and Hacking, A. (1974) The occurrence and effects of mycotoxins in animal feedstuffs in the UK. Agricultural Development and Advisory Service, Ministry of Agriculture, Fisheries and Food Science Arm. Ann. Rep. 1972, HMSO London, p. 73Google Scholar
  25. Hoshina, T., Sano, T. and Sunayama, M. (1960) Studies on the saprolegniasis of eel.J. Tokyo Univ. Fish., 47, p. 59Google Scholar
  26. Jager (1816) Ueber die Entstehung von Schimmel im Innern des thierischen korpers. Deut. Arch. Anat. u. Physiol. (Meckel), 2, p. 354Google Scholar
  27. Lancaster, M.C., Jenkins, F.P. and Philp, J.M. (1961) Toxicity associated with certain samples of groundnuts. Nature, 192, pp. 1095–6CrossRefGoogle Scholar
  28. Langeron, M. (1922) Utilite de deux nouvelles coupures generiques dans les Perisporiaces: Diplostephanus n. gen. et Carpenteles n. gen. Compt. rend. Soc. biol., 87, pp. 343–5Google Scholar
  29. Link, H.F. (1809) Observations in Ordines plantarum naturales. Gesellschaft Naturforschender Freunde zu Berlin, Magazin 3, pp. 1–42 (cited as ‘Link, observations I’)Google Scholar
  30. Majeed, S.K., Jolly, D.W. and Gopinath, C. (1984) An outbreak of liver cell carcinoma in rainbow trout, Salmo gairdneri Richardson, in the UK. J. Fish Dis. 7, pp. 165–8CrossRefGoogle Scholar
  31. Marsalek, E., Zizka, A., Riha, V., Dusek, J. and Dvoracek, C. (1960) Plicni aspergilloza s gneralizaci vyvolana druhem Aspergillus restrictus. Casopis lekaru ceskych, 99, pp. 1285–92Google Scholar
  32. Mayer, A.C. and Emmert, V.L. (1815) Verschimmelung (Mucedo) im lebenden korper. Deut. Arch. Anat. U. Physiol. (Meckel), 1, p. 310Google Scholar
  33. Mayr, G. (1973) Untersuchen über der Wirkung von Arthelynoxid zur Beseitung von Schimmelpilzen. Doctoral thesis. Friedrich Wilhelms Universität du Bonn. Germany. 412 ppGoogle Scholar
  34. Micheli, P.A. (1729) Nova plantarum genera juxta Tournefortii methodum disposita, Florence, 234 ppGoogle Scholar
  35. Miller, M.W. (1961) The Pfizer Handbook of Microbiol Metabolites. McGraw-Hill, New York, 772 ppGoogle Scholar
  36. Montague, G. (1813) Supplement to the Ornithological Dictionary (1802). Woolmann, LondonGoogle Scholar
  37. Moss, M.O. (1977) Aspergillus mycotoxins, in Smith, T.E. and Paterman, J.A. (eds.) Genetics and Physiology of Aspergillus, Academic Press, London, pp. 499–524Google Scholar
  38. Olufemi, B.E. (1984) Aspergillus in cultured tilapias. PhD thesis, University of StirlingGoogle Scholar
  39. Olufemi, B.E., Agius, C. and Roberts, R.J. (1983) Aspergillomycosis in intensively cultured tilapia from Kenya. Vet. Rec, 112, pp. 203–4CrossRefGoogle Scholar
  40. Olufemi, B.E. and Roberts, R.J. (1983) Method for the isolation of Aspergillus species pathogens of fish from clinical materials. Vet. Rec, 112, p. 15CrossRefGoogle Scholar
  41. Paterson, J.S., Crook, J.C., Shand, A., Lewis, G. and Allcroft, R. (1962) Groundnut toxicity as the cause of exudative hepatitis (oedema disease) of guinea-pigs. Vet. Rec, 74, pp. 639–40Google Scholar
  42. Porter, B.M., Comfort, B.K., Menges, R.W., Habermann, R.T. and Smith, C.D. (1965) Correlation of fluorescent antibody, histopathology and culture on tissues from 372 animals examined for histoplasmosis and blastomycosis. J. Bad., 89, pp. 748–51Google Scholar
  43. Price, C.R. (1981) A study of aflatoxin in tilapia feedstuffs. MSc dissertation. University of Stirling, V -I- 51 ppGoogle Scholar
  44. Raper, K.B. and Fennell, D.I. (1965) The Genus Aspergillus, Williams and Wilkins, Baltimore, 686 ppGoogle Scholar
  45. Rayer and Montagne (1842) Mycose aspergillaire dans les poches aériennes d’un bouvreuil. J. inst. Paris, p. 270, Müllers Arch. 1842, p. 270Google Scholar
  46. Richards, R.H. (1978) Mycology of teleosts in R.J. Roberts (ed.), Fish Pathology, Bailliere-Tindall, London, 328 ppGoogle Scholar
  47. Rogers, A.E. and Newberne, P.M. (1967) The effects of aflatoxin B, and dimethylsulfoxide on thymidine — 3H uptake and mitosis in rat liver. Cancer Res., 27, pp. 855–64Google Scholar
  48. Rousseau, E. and Serrurier, F. (1841) Developpement de cryptogames sur les tissus de vertebres vivants. Compt. rend., 13, pp. 18–19Google Scholar
  49. Sargeant K., Sheridan, A., O’Kelly, J. and Carnaghan, B.A. (1961) Toxicity associated with certain samples of groundnuts. Nature, 192, pp. 1096–7CrossRefGoogle Scholar
  50. Scott, W.W. (1964) Fungi associated with fish diseases. Devel. Ind. Microbiol, 5, pp. 109–23Google Scholar
  51. Siebenmann, F. (1889) Die schimmelmykosen des menschlichen ohres, Bergmann, Wiesbaden, 118 ppGoogle Scholar
  52. Sinnhuber, R.O., Wales, J.H., Ayres, J.L., Engebrecht, R.H. and Amend, D.L. (1968) Dietary factors and hepatoma in rainbow trout (Salmo gairdneri). I. Aflatoxins in vegetable protein feedstuffs. J. Natl. Cancer. Inst., 41, pp. 711–18Google Scholar
  53. Spegazzini, C. (1911) Aspergillopsis. Anales musco nacl. Buenos Aires, Sev. 3, 13, p. 434Google Scholar
  54. Spensley, P.C. (1963) Aflatoxin, the active principle in Turkey ‘X’ disease, Endeavor, 22, pp. 75–9CrossRefGoogle Scholar
  55. Thorn, C. and Church, M.B. (1926) The Aspergilli. Williams and Wilkins, Baltimore, 272 ppGoogle Scholar
  56. Thorn, C. and Raper, K.B. (1945) A Manual of the Aspergilli. Williams and Wilkins, Baltimore, 373 ppGoogle Scholar
  57. Tiffney, W.N. (1939) The host range of Saprolegnia parasitica Mycologia, 31, p. 310CrossRefGoogle Scholar
  58. Virchow, R. (1865) Beitrage zur Lehre von den beim Menschen vorkommenden pflanzlichen Parasiten. Arch, pathol. Anat. U. Physiol. Virchow’s, 9, pp. 557–93CrossRefGoogle Scholar
  59. Vishniac, J.F. and Nigrelli, R.F. (1957) The ability of the Saprolegniaceae to parasitize platyfish. Zoologica (New York), 43, p. 131Google Scholar
  60. Wales, J.H. and Sinnhuber, R.O. (1966) An early hepatoma epizootic in rainbow trout, Salmo gairdnerii. Calif. Fish and Game, 52, pp. 85–91Google Scholar
  61. Wales, J.H. (1967) Degeneration and regeneration of liver parenchyma accompanying hepatomagenesis. Trout Hepatoma Research Conference Papers. US Fish and Wildl. Serv., Res. Rep., 70, pp. 56–9Google Scholar
  62. Wales, J.H. (1970) Hepatoma in rainbow trout, in S.F. Snieszko (ed.), A Symposium on Diseases of Fishes and Shellfishes, American Fisheries Society, New York, pp. 351–65Google Scholar
  63. Wales, J.H. (1979) Induction of hepatoma in rainbow trout Salmo gairdneri Richardson by the egg bath technique. J. Fish Dis., 2, pp. 563–6CrossRefGoogle Scholar
  64. Wehmer, C. (1901) Die Pilzgattung Aspergillus in morphologischer physiologischer und systematischer Beziehung. Mem. Soc. phys. hist. nat. Geneva, 33, pp. 1–157 (Commonly cited as Wehmer’s Monograph)Google Scholar
  65. Wolf, H. and Jackson, E.W. (1963) Hepatoma in rainbow trout: descriptive and experimental epidemiology. Science, 142, pp. 676–8CrossRefGoogle Scholar
  66. Wolf, H. and Jackson, E.W. (1967) Hepatoma in salmonids: the role of cottonseed products and species differences. Trout Hepatoma Research Conference Papers. US Fish and Wildl. Serv. Res. Rep., 70, pp. 29–33Google Scholar
  67. Wolke, R.E. (1975) Pathology of bacterial and fungal diseases, in Ribelin, W.E. and Migaki, G.. The Pathology of Fishes, University of Wisconsin Press, Madison, pp. 33–116Google Scholar
  68. Wood, E.M., Vasutake, W.T. and Lenihan, W.C. (1955) A mycosis like granuloma of fish. J. Infect. Dis., 97, pp. 262–7CrossRefGoogle Scholar

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© James F. Muir and Ronald J. Roberts 1985

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  • Benjamin E. Olufemi

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