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DNA Methylation and DNA Structure

  • S. Spadari
  • G. Pedrali-Noy
  • M. Ciomei
  • A. Rebuzzini
  • U. Hübscher
  • G. Ciarrocchi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 179)

Abstract

Novel DNA substrates, such as hemimethylated DNA, supercoiled, partially or fully relaxed DNA, either intact or UV-irradiated, have been used to study either some aspects of the mechanism of DNA methylation or some aspects of the effect of pathological and physiological DNA methylation on DNA conformation.

Keywords

Methyl Methane Sulfonate Superhelical Turn HpaII Endonuclease Unmethylated Control DNAs Electrophoretic Mobi 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Spanos, A. and Hübscher, U. (1983) in: Methods in Enzymology (Hirs, C.W.S. and Timasheff, S.N., eds.) Academic Press, New York 91, 265.Google Scholar
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • S. Spadari
    • 1
  • G. Pedrali-Noy
    • 1
  • M. Ciomei
    • 1
  • A. Rebuzzini
    • 1
  • U. Hübscher
    • 2
  • G. Ciarrocchi
    • 1
  1. 1.Istituto di Genetica Biochimica ed EvoluzionisticaC.N.R.PaviaItaly
  2. 2.Institut für Pharmakologie und BiochemieUniversität Zürich-IrchelZürichSwitzerland

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