Interaction of DNA Accessory Proteins with DNA Polymerase β of the Novikoff Hepatoma

  • R. R. Meyer
  • D. C. Thomas
  • T. J. Koerner
  • D. C. Rein
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 179)


Replication and repair require the concerted action of a DNA polymerase with several accessory proteins. In prokaryotes the interaction of such proteins in replication has been well documented (1). With DNA repair, less is known, although with the recent progress of the uvr system of Escherichia coli we can anticipate a better understanding of excision-repair in bacteria (2). In eukaryotes there is a wealth of information on polymerases, but little progress has been made with mechanistic studies of accessory proteins for replication or repair.


Accessory Protein Strand Displacement Template Strand Novikoff Hepatoma Apyrimidinic Site 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Kornberg, A. (1980) “DNA Replication”, W.H. Freeman Co., San Francisco.Google Scholar
  2. 2.
    Sancar, A. and Rupp, W.D. (1983) Cell 33, 249.PubMedCrossRefGoogle Scholar
  3. 3.
    Probst, G.S., Stalker, D.M., Mosbaugh, D.W. and Meyer, R.R. (1975) Proc. Natl. Acad. Sci. USA 72, 1171.PubMedCrossRefGoogle Scholar
  4. 4.
    Mosbaugh, D.W., Stalker, D.M. and Meyer, R.R. (1977) Biochemistry 16, 1512.PubMedCrossRefGoogle Scholar
  5. 5.
    Stalker, D.M., Mosbaugh, D.W. and Meyer, R.R. (1976) Biochemistry 15, 3114.PubMedCrossRefGoogle Scholar
  6. 6.
    Mosbaugh, D.W. and Meyer, R.R. (1980) J. Biol. Chem. 255, 10239.PubMedGoogle Scholar
  7. 7.
    Koerner, T.J. and Meyer, R.R. (1983) J. Biol. Chem. 258, 3126.PubMedGoogle Scholar
  8. 8.
    Thomas, D.C. and Meyer, R.R. (1982) Biochemistry 21, 5060.PubMedCrossRefGoogle Scholar
  9. 9.
    Meyer, R.R., Glassberg, J., Scott, J.V. and Kornberg, A. (1980) J. Biol. Chem. 258, 2897.Google Scholar
  10. 10.
    Banks, G.R., Spanos, A., Kairis, M.V. and Molineux, I.J. (1981) J. Mol. Biol. 151, 321.PubMedCrossRefGoogle Scholar
  11. 11.
    Pedrini, A.M. and Grossman, L. (1983) J. Biol. Chem. 258, 1536.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • R. R. Meyer
    • 1
  • D. C. Thomas
    • 1
  • T. J. Koerner
    • 1
  • D. C. Rein
    • 1
  1. 1.Department of Biological SciencesUniversity of CincinnatiCincinnatiUSA

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