Interaction of DNA Accessory Proteins with DNA Polymerase β of the Novikoff Hepatoma
Replication and repair require the concerted action of a DNA polymerase with several accessory proteins. In prokaryotes the interaction of such proteins in replication has been well documented (1). With DNA repair, less is known, although with the recent progress of the uvr system of Escherichia coli we can anticipate a better understanding of excision-repair in bacteria (2). In eukaryotes there is a wealth of information on polymerases, but little progress has been made with mechanistic studies of accessory proteins for replication or repair.
KeywordsAccessory Protein Strand Displacement Template Strand Novikoff Hepatoma Apyrimidinic Site
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