Aphidicolin and Eukaryotic DNA Synthesis

  • Silvio Spadari
  • Francesco Sala
  • Guido Pedrali-Noy
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 179)


Animal cells are endowed with two sites containing DNA: nucleus and mitochondrion. Plant cells are more complex in this respect: they contain also plastids. The DNAs of nucleus, mitochondrion and plastid differ in structural organization as well as in the mode of replication. Furthermore both animal and plant cells are able to repair damaged nuclear DNA. So it is not surprising that different DNA polymerases are involved in the different types of DNA synthesis occurring in the three distinct cellular site (1).


Spleen Lymphocyte Plant Cell Report Rabbit Bone Marrow Nicotiana Sylvestris Aphidicolin Treatment 
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • Silvio Spadari
    • 1
  • Francesco Sala
    • 1
  • Guido Pedrali-Noy
    • 1
  1. 1.Istituto di Genetica Biochimica ed Evoluzionistica del C.N.R.PaviaItaly

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