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Correlation Between Hydroxyindole-O-Methyl Transferase Rhythmicity and Reproductive Function in the Rat

  • J. M. Yochim
  • E. P. Wallen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 54)

Abstract

Dr. Wallen has presented a simplified mathematical model of hydroxy-indole- O-methyltransferase (HIOMT) activity which can account for physiological changes in enzyme activity imposed by (a) the presence or absence of ovarian hormones, (b) the application of neuroendocrine stimuli such as the induction of pseudopregnancy, and (c) a change in the proportion of light per day (Wallen and Yochim, 1973a, b; Yochim and Wallen, 1973a,b). These effects could be simulated by changing the numerical value of one or more terms on a mixed-wave equation.

Keywords

Pineal Gland Estrous Cycle Reproductive Function Endogenous Rhythm Beat Period 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Wallen, E. P. and Yochim, J. M. (1973a). Rhythmic function of pineal hydroxyindole-O-methyl transferase during the estrous cycle: an analysis. Biology of Reproduction. In press.Google Scholar
  2. Wallen, E. P. and Yochim, J. M. (1973b). Pineal HIOMT activity in the rat: effect of ovariectomy and hormone replacement. Biology of Reproduction. In press.Google Scholar
  3. Wallen, E. P. and Yochim, J. M. (1973c). Photoperiodic regulation of the estrous cycle of the rat: role of the pineal gland. Biology of Reproduction. In press.Google Scholar
  4. Yochim, J. M. and Wallen, E. P. (1973a). HIOMT activity in the pineal gland of the female rat: effects of light. Biol. Reprod. In press.Google Scholar
  5. Yochim, J. M. and Wallen, E. P. (1973b). Function of the pineal gland of the rat during progestation: alterations in HIOMT rhythmicity. Biol. Reprod. In press.Google Scholar
  6. Yochim, J. M. and Wallen, E. P. (1973c). Photoperiod, pineal HIOMT activity and reproductive function in the rat: a proposed model. Biol. Reprod. In press.Google Scholar

Discussion References

  1. Cole, L. C. (1957). Science 125, 874–376.PubMedCrossRefGoogle Scholar
  2. Crowley T., Kripke, D., Halberg, F., Pegram, G., and Schildkrauc, J. (1972). Primates 13, 149–168.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • J. M. Yochim
    • 1
  • E. P. Wallen
    • 1
  1. 1.Department of Physiology and Cell BiologyUniversity of KansasLawrenceUSA

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