An Analysis of the Pineal Hydroxyindole-O-Methyl Transferase Rhythm During the Estrous Cycle of the Rat
For the past few years our laboratory has been interested in the relationship between pineal gland rhythmicity and reproductive function in the rat. As an index of pineal rhythmicity we followed the diurnal variations in hydroxyindole-O-methyl transferase (HIOMT), the enzyme which forms melatonin, one of the pineal’s antigonadotropic hormones. We have interpreted the effects of endocrine and environmental manipulation in terms of changes in a mixed-wave equation.
KeywordsPineal Gland Estrous Cycle Ovarian Hormone Thetical Rhythm Continuous Darkness
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