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Gene Expression in the Early Mouse Embryo and Cultured Cells

  • Markku Kurkinen
Part of the Basic Life Sciences book series (BLSC, volume 48)

Abstract

Development of the early mouse embryo has been described in great detail and provides the basis for studies in elucidating how cellular differentiation processes are programmed and coordinated during mammalian development. To this end, it has been important to isolate and characterize cell- and tissue-specific markers, genes and their products, which are expressed in early mouse embryogenesis. Indeed, a number of such markers have been identified and some of them can be used to distinguish the appearance of the very first differentiated cell types. An understanding of how and why these markers are selectively expressed during development, it seems, is a first step in finding out the molecular basis for differentiation processes.

Keywords

Embryonic Stem Cell Line Endoderm Cell Embryonal Carcinoma Cell Basement Membrane Component Visceral Endoderm 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Markku Kurkinen
    • 1
  1. 1.Department of MedicineUniv. of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical SchoolPiscatawayUSA

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