X-Ray Emission Quantitation of Trace Elements in Biomedical Research

  • Marvin Goldman
  • E. D. Beckman
Part of the Developments in Applied Spectroscopy book series (DAIS, volume 6)


Determination of trace-element concentrations in biologic materials is often limited by matrix effects and interelement interferences. X-ray spectrometry can provide rapid, nondestructive quantitation of trace metals at the parts per million level. Derivation of empirical absorption coefficients by utilizing standardized specimen preparation can optimize the precision and accuracy of determinations. The specimen is used as an absorber of the characteristic wavelength of the element to be quantitated and provides an index of the excitation efficiency essential to the quantitation of emission intensity. Food and tissue specimens were analyzed and the results compared with those obtained by other analytical methods. Calibration techniques using internal and reference standards are illustrated. Determinations of Ca, Sr, Zn, Tl, Se, Fe, I, and Ti were applied to the study of specific problems in metabolic, geriatric, and cancer research.


Strontium Content Mass Absorption Coefficient Fluorescent Radiation Calcium Removal Zinc Oxalate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Chicago Section of the Society for Applied Spectroscopy 1968

Authors and Affiliations

  • Marvin Goldman
    • 1
  • E. D. Beckman
    • 1
  1. 1.Radiobiology LaboratoryUniversity of CaliforniaDavisUSA

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