The Use of Thin-Layer Chromatography With Infrared Spectroscopy

  • Marcia K. Snavely
  • Jeanette G. Grasselli
Conference paper
Part of the Developments in Applied Spectroscopy book series (DAIS, volume 3)


Thin-layer chromatography is a fast and economical way of separating mixtures of non-volatile liquids or solids. It requires only a small amount of sample and is applicable to problems in diversified fields. It serves as a useful complement to column and paper chromatography, and, like these methods, it requires some other analytical tool for positive identification of the separated components. In this work infrared spectroscopy has been used with thin-layer chromatography to analyze synthetic mixtures, organic reaction products, and commercial samples. Several techniques for obtaining IR spectra from the thin-layer spots will be described, and special methods of preparing the thin-layer plates will be recommended. The combined use of these two tools holds unique advantages and is certain to be employed even more frequently in the analytical and research laboratories.


Metal Carbonyl Gene Rally Commercial Plasticizer Diallyl Phthalate Zinc Dithiophosphate 
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Copyright information

© Chicago Section of the Society for Applied Spectroscopy 1964

Authors and Affiliations

  • Marcia K. Snavely
    • 1
  • Jeanette G. Grasselli
    • 1
  1. 1.Chemical and Physical Research DepartmentThe Standard Oil Company (Ohio)ClevelandUSA

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