Choline Uptake in Nerve Cultures and in Synaptosomal Preparation is Regulated by the Endogenous Pool of Choline
Several experimental reports have, in the past, indicated that choline (Ch) is not synthesized in nerve cells through the mechanisms which are present in the liver, i.e. methylation of free ethanolamine or of ethanolamine containing phospholipids (for a review see 3). However, in 1972 Dross and Kewitz (2) showed that Ch may be produced in the brain.
KeywordsCholine Uptake Synaptosomal Preparation Choline Acetyl Crude Synaptosomal Fraction Mixed Primary Culture
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