Synthesis of Choline in the Brain

  • H. Kewitz
  • O. Pleul
Part of the Advances in Behavioral Biology book series (ABBI, volume 25)


Specific radioactivities of choline (Ch), phosphorylcholine (PCh), lecithin, lysolecithin and glycerylphosphorylcholine (GPCH) have been measured in blood, liver, muscle, and including acetylcholine (ACh) in brain after injection (i.v) of three labelled precursors, Ch, the methyl group of methionine and ethanolamine. In relation to the specific activity of Ch in blood there was significantly more radioactivity in the Ch of brain after labelled methyl groups and labelled ethanolamine than after labelled Ch.


Turnover Rate Pool Size Specific Radioactivity Venous Blood Flow Arterial Blood Supply 


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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • H. Kewitz
    • 1
  • O. Pleul
    • 1
  1. 1.Department of Clinical PharmacologyFree University of BerlinBerlin 45West Germany

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