The Regional Distribution of Acetylcholine, Cholinacetyltransferase, and Acetylcholinesterase in Vertebrate Brains of Different Phylogenetic Levels

  • K. Wachtler
Part of the Advances in Behavioral Biology book series (ABBI, volume 25)


Comparative data on the occurrance and regional distribution of acetylcholine (ACh) and its enzymes cholinacetyltransferase (ChAT) and acetylcholinesterase (AChE) in the vertebrate brains have been reported by several authors (for reviews see 3,4). Recent observations restricted to the determination of ChAT and AChE in a variety of species can be found in several papers (6,10,13–16). In the present paper an attempt to survey the regional distribution of cholinergic components in vertebrates under phylogenetic aspects is made. The data presented here were obtained from whole brains and brain regions of 27 vertebrates, in most of which all three components (ACh, Chat and AChE) were determined. In the selection of species to be studied efforts were made to cover the main lines of vertebrate evolution, which are indicated in Fig. 1.


Regional Distribution AChE Activity Cholinergic Activity ChAT Activity Vertebrate Brain 
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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • K. Wachtler
    • 1
  1. 1.Institut fur ZoologieTeirarztlichen Hochschule3 Hannover 1Germany

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