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Early Effects of Denervation on Acetylcholine and Choline Acetyltransferase in Skeletal Muscle

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Part of the book series: Advances in Behavioral Biology ((ABBI,volume 25))

Abstract

The effects of motor nerve section on the physiology and ultrastructure of nerve and muscle have been studied in great detail (see for instance 2,18,27). After a delay which is dependent on the length of the nerve stump, the transmission of impulses fails, due to disintegration of motor nerve terminals. At this time motor axons still conduct impulses but they also degenerate later after denervation. In the frog the muscle membrane at the junctions is not left naked because Schwann cells take the place previously occupied by the motor terminals. In the rat this occurs only transiently.

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© 1981 Plenum Press, New York

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Miledi, R., Molenaar, P.C., Polak, R.L. (1981). Early Effects of Denervation on Acetylcholine and Choline Acetyltransferase in Skeletal Muscle. In: Pepeu, G., Ladinsky, H. (eds) Cholinergic Mechanisms. Advances in Behavioral Biology, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8643-8_20

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  • DOI: https://doi.org/10.1007/978-1-4684-8643-8_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8645-2

  • Online ISBN: 978-1-4684-8643-8

  • eBook Packages: Springer Book Archive

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