Effect of Latrodectus Mactans Tredecimguttatus Venom on Synaptic Transmission of Chicken Ciliary Ganglion in Vitro

  • L. Bolzoni
  • A. Meneguz
  • P. Paggi
Part of the Advances in Behavioral Biology book series (ABBI, volume 25)


The venom of the black widow spider (BWSV), Latrodectus mactans tredecimguttatus, contains a neurotoxin causing a massive transmitter release from various vertebrate terminals (3,6,9,13). The pharmacological and physiological effects of this venom, in vivo and in vitro, are well known (1,7,15). On the other hand, its mechanism of action is still not clear, despite the fact that much evidence on the mode of action of this venom at vertebrate neuromuscular junctions has been collected in recent years (5). Some insight into this problem was furnished by previous investigations on the rat sympathetic ganglion (13,14).


Ciliary Cell Electrical Coupling Ciliary Ganglion Parasympathetic Ganglion Cell BioI 


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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • L. Bolzoni
    • 1
  • A. Meneguz
    • 2
  • P. Paggi
    • 1
  1. 1.Istituto di Fisiologia GeneraleUniversita di RomaItaly
  2. 2.Istituto Superiore di SanitaRomaItaly

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