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Effect of Latrodectus Mactans Tredecimguttatus Venom on Synaptic Transmission of Chicken Ciliary Ganglion in Vitro

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Cholinergic Mechanisms

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 25))

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Abstract

The venom of the black widow spider (BWSV), Latrodectus mactans tredecimguttatus, contains a neurotoxin causing a massive transmitter release from various vertebrate terminals (3,6,9,13). The pharmacological and physiological effects of this venom, in vivo and in vitro, are well known (1,7,15). On the other hand, its mechanism of action is still not clear, despite the fact that much evidence on the mode of action of this venom at vertebrate neuromuscular junctions has been collected in recent years (5). Some insight into this problem was furnished by previous investigations on the rat sympathetic ganglion (13,14).

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© 1981 Plenum Press, New York

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Bolzoni, L., Meneguz, A., Paggi, P. (1981). Effect of Latrodectus Mactans Tredecimguttatus Venom on Synaptic Transmission of Chicken Ciliary Ganglion in Vitro . In: Pepeu, G., Ladinsky, H. (eds) Cholinergic Mechanisms. Advances in Behavioral Biology, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8643-8_14

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  • DOI: https://doi.org/10.1007/978-1-4684-8643-8_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8645-2

  • Online ISBN: 978-1-4684-8643-8

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