Oxidation-Reduction Associated with Inhaled NO2 Absorption

  • Mohammad G. Mustafa


NO2 is a free radical and powerful oxidant, which is reduced to NO2 - in the lung; NO2 - is then oxidized to NO3 - in the blood. NO2 in the presence of O3 produces N2O5 (anhydride of HNO3) and NO3 (a free radical), which are more toxic than NO2. A synergism that is observed in the toxicity of NO2 plus O3, compared to NO2 or O3 alone, may be explained on the basis of N2O5 and NO3 formation.


Lung Tissue Photochemical Smog Free Radical Chain Reaction Election Donor Isolate Perfuse Lung 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Mohammad G. Mustafa
    • 1
  1. 1.Division of Enviromental and Occupational Health Sciences School of Public HealthUniversity of CaliforniaLos AngelesUSA

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