The Correlation between Structure and Tritium Incorporation During Labeling by the Wilzbach Method

  • L. Träger
  • A. Wacker


Many attempts have been made to find a pattern for tritium incorporation during Wilzbach labeling of organic molecules [1]. Unfortunately, it is still imposible to make more than a rough prediction about tritium incorporation.


INCORPORA TION Imine Form Nuclear Corporation High Tritium Amino Form 
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  1. 1.
    Wenzel, M., and Schulze, P. E., Tritium-Markierung, Darstellung, Messung und Anwendung nach Wilzbach Tritium-markierter Verbindungen, Walter de Gruyter, Berlin, 1962.Google Scholar
  2. 2.
    Wilzbach, K.E., J. Am. Chem. Soc. 79: 1013 (1957).CrossRefGoogle Scholar
  3. 3.
    Wacker, A., and Träger, L., Angew. Chem. 72: 168 (1960).CrossRefGoogle Scholar
  4. 4.
    Wacker, A., in Davidson, J.N., and Cohn, W. E. (editors), Progress in Nucleic Acid Research, Vol. 1, Academic Press, New York, 1963, p. 369.Google Scholar
  5. 5.
    Garnett, J.L., and Sollich W.A., Nature 201: 902 (1964).CrossRefGoogle Scholar

Copyright information

© New England Nuclear Corporation 1966

Authors and Affiliations

  • L. Träger
    • 1
  • A. Wacker
    • 1
  1. 1.Institute of Therapeutic BiochemistryUniversity of FrankfurtFrankfurt am MainGermany

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