Use of Vinyl Magnesium Bromide in the Synthesis of Labeled Compounds: New Preparations of Glycerol-1-C14 and Glyceric Acid-1-C14
The biological importance of glycerol and glyceric acid is well known; as a consequence, it is very useful to have methods for the labeling of these compounds ith C14. An improved method for the synthesis of glyceric acid-1-C14 has recently been described by Ashworth in England . However, especially in the case of glycerol, the published methods are time-consuming and the overall yield is fairly low.
KeywordsAcrylic Acid Methyl Acrylate Allyl Alcohol Grignard Reagent Potassium Acetate
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Ashworth, J. M., J. Chem. Soc. 2563 (1963).Google Scholar
Normant, H., Bull. Soc. Chim. France 728 (1957).Google Scholar
Sulima, L. V., Chem. Abst. 57: 12302a (1962).Google Scholar
Benedict, G. E., and Russell, R. R., J. Am. Chem. Soc. 73: 5444 (1951).CrossRefGoogle Scholar
Pajaro, G., and Valvassori, A., Gazz. Chim. Italiana 92: 1446 (1962).Google Scholar
Hochstein, F. A., and Brown, W.G., J. Am. Chem. Soc. 70: 3484 (1948).CrossRefGoogle Scholar
Nystrom, R. F., J. Am. Chem. Soc. 81: 610 (1959).CrossRefGoogle Scholar
Pichat, L., Herbert, M., and Aubert, F., J. Labelled Compds. 1: 66 (1965).CrossRefGoogle Scholar
© New England Nuclear Corporation 1966