Nucleic Acid Metabolism during Antibody Synthesis in Vitro
Earlier experiments have shown that spleen cells isolated from rabbits immunized with alcohol dehydrogenase synthesize antibodies against the enzyme for as long as 50 hours [1,2]. We investigated the influence of various antimetabolites on this antibody synthesis. Among other results, we found a complete inhibition by puromycin and actinomycin D.
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