Application of Double Isotope Labeling to the Study of the Metabolism of Ascites Tumor Cells under the Influence of Glyceraldehyde
There are many reports in the literature dealing with the metabolic fate of the carbon atoms of glucose in various tissues. Little is known, however, about the metabolic fate of distinct hydrogen atoms of the glucose molecule in normal or tumor tissues. Such information may have special significance with respect to understanding the abnormal growth characteristics of malignant tissues, since these hydrogen atoms are not only oxidized to water, but also can be used for the reduction of organic substrates.
KeywordsBiochemical Application Ascites Cell Oxaloacetic Acid Ketoglutaric Acid Glucose Metabolite
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