Coordinated Design of Radioisotope Laboratories
Recent advances in the use of radioisotopes as a research tool have broadened the scope of the field and have created the need for specially designed laboratories to handle more hazardous operations. Although low-level experiments can be and are being carried out in conventional laboratories, these laboratories are generally inadequate to accommodate operations involving higher levels of radioactivity. Notable examples in this regard are: use of the Wilzbach method in the preparation of tritium-labeled compounds, use of radioisotopes in studies with large animals (problems in waste control), and the use of biosynthetic methods to prepare carbon-14-labeled compounds having a high specific activity. These operations may involve curies of tritium gas, tens or hundreds of millicuries of carbon-14, and the use of gamma emitters at multimillicurie levels.
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- 1.The Architectural Approach to Radiochemical Laboratory Design,“ A.D. Mackintosh, U.S. Atomic Energy Commission Report AECU-210 (ORNL-335) 1949.Google Scholar
- 2.Symposium on Radiochemistry Laboratories, Ind. Eng. Chem. 41, 228 (1949) P. C. Thompkins and H. A. Levy, “The Impact of Radioactivity on Chemical Laboratory Techniques and Design”; W. P. Norris, “Radiobiochemical Laboratories”; J. W. Swartout, “Research with Low Levels of Radioactivity”; N.B. Garden, “Semihot Laboratories”; P.C. Tompkins, “A Radioisotope Building”; C. N. Rice, “Laboratory for Preparation and Use of Radioactive Organic Compounds”; H. A. Levy, “Remodeling a Laboratory for Radiochemical Instruction or Research.”CrossRefGoogle Scholar
- 3.Design and Construction of Radiochemical Laboratories,“ a selected list of unclassified references (TIC-3013) Technical Information Services, Oak Ridge, Tennessee (1951).Google Scholar
- 4.Radioisotopes in Biology and Agriculture,“ Comar, in: Facilities and Handling of Radioisotopes with Animals and Plants, McGraw-Hill Publishing Co., New York, pp. 114–57, 1955.Google Scholar
- 5.A Selected Reading List on Radiological Protection and Laboratory Design-1946 to 1956,“ R. J. Millet, Isotope Division A.E.R.E., Harwell, England (1956).Google Scholar
- 6.Construction of Laboratory Buildings,“ Anal. Chem. 34,-pp. 25A–46A (1962).Google Scholar
- 7.Low Level Radioisotope Laboratories,“ Donald R. Ward, a chapter in Laboratory Planning for Chemistry and Chemical Engineering, edited byHarry F. Lewis, Reinhold Publishing Corp., New York, pp. 156–170, 1962.Google Scholar