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Diisopropylfluorophosphate-P32 (DFP-P32) as a Label for Granulocytes

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Abstract

Diisopropylfluorophosphate (DFP), a potent and irreversible esterate inhibitor, was first suggested as a red cell label by Grob, Lilienthal, Harvey, and Jones in 1947 [1]. In 1954 Cohen and Warringa [2] described the use of DFP containing radioactive phosphorous (DFP-P32) as a label for erythrocytes, and two years later Leeksma and Cohen [3] described the use of DFP-P32 as a platelet label. The latter authors found relatively little label in leukocytes.

Presented at the Sixth Symposium on Advances in Tracer Methodology, November, 1962.

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References

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© 1965 New England Nuclear Corporation

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Raab, S.O. (1965). Diisopropylfluorophosphate-P32 (DFP-P32) as a Label for Granulocytes. In: Rothchild, S. (eds) Advances in Tracer Methodology. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-8622-3_30

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  • DOI: https://doi.org/10.1007/978-1-4684-8622-3_30

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-8624-7

  • Online ISBN: 978-1-4684-8622-3

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