Steroid Secretory Mixtures in Man

  • Edward G. Biglieri


The simultaneous determination of the secretory rates of the major adrenal hormones, cortisol, corticosterone, and aldosterone, should provide the critical information necessary to evaluate their individual and collective roles in certain clinical disorders. These procedures have been made feasible by:(1) the availability of radioactive steroids of sufficient stability and specific activity so that the amount injected is not large enough to alter normal transport and metabolism, and (2) the development of techniques to assess their rate of secretion [1–5]


Adrenal Gland Primary Aldosteronism Aldosterone Secretion Adrenal Tissue Normal Transport 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Cope, C. L., and Black, E.G., Clin. Sci. 17: 147 (1958).Google Scholar
  2. 2.
    Peterson, R. E., Recent Progr. Hormone Res. 15: 231 (1959).Google Scholar
  3. 3.
    Flood, C., Layne, D. S., Ramcharan, S., Rossipal, E., Tait, J. F., and Tait, S. A. S., Acta. Endocrinol 36: 237 (1961).Google Scholar
  4. 4.
    Peterson, R, E., and Pierce, C E., J. Clin. Invest. 39: 741 (1960).Google Scholar
  5. 5.
    Ulick, S., Laragh, J. H., Lieberman, S., Trans. Assoc. Am. Physicians 71: 225 (1958).Google Scholar
  6. 6.
    Biglieri, E.G., Hane, S., Slaton, P. E., Jr., and Forsham, P.H., J. Clin. Invest. 42: 516 (1963).CrossRefGoogle Scholar
  7. 7.
    Kliman, B., and Peterson, R. E., J. Biol. Chem. 235: 1639 (1960).Google Scholar
  8. 8.
    Neher, R., in: An International Symposium on Aldosterone ( A. F. Muller and C.M. O’Connor, eds.) Little, Brown, Boston (1958), p. 11.Google Scholar
  9. 9.
    Hellman, L., Bradlow, H. L., Zumoff, B., Gallagher, T. F., J. Clin. Endocrin. Metab. 21: 1231 (1961).CrossRefGoogle Scholar
  10. 10.
    Meador, C. K., Liddle, G. W., Island, D.P., Nicholson, W. E., Lucas, C. P., Nuckton, J.G., and Luetscher, J. A., J. Clin. Endocr. 22: 693 (1962).CrossRefGoogle Scholar

Copyright information

© New England Nuclear Corporation 1965

Authors and Affiliations

  • Edward G. Biglieri
    • 1
  1. 1.San Francisco General HospitalUniversity of California ServiceSan FranciscoUSA

Personalised recommendations