Use of Labeled Nonmetabolized Amino Acids in Biochemical Research

  • Thomas R. Riggs
  • Halvor N. Christensen


The biochemical investigator usually is pleased to find that a large quantity of C14 or other tracer atom has been transferred from his starting compound to another substance. This article will consider a group of compounds for which metabolic modification to other substances can scarcely be detected, and the experimental applications which this property may permit.


Biochemical Application Amino Acid Transport Amino Acid Transport System Aminoisobutyric Acid Model Amino Acid 


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  1. 1.
    Christensen, H.N., and Jones, J. C., J. Biol. Chem. 237: 1203 (1962).Google Scholar
  2. 2.
    Christensen, H. N., and Clifford, J. B., Biochim. Biophys. Acta 62: 160 (1962).CrossRefGoogle Scholar
  3. 3.
    Christensen, H. N., Feldman, B. H., and Hastings, A.B., Am. J. Physiol. 205: 255 (1963).Google Scholar
  4. 4.
    Reddy, D. V. N., and Kinsey, V. E., Invest. Ophth. 2: 237 (1963).Google Scholar
  5. 5.
    Noall, M. W., Riggs, T. R., Walker, L.M., and Christensen, H.N., Science 126: 1002 (1957).CrossRefGoogle Scholar
  6. 6.
    Riggs, T. R., and Walker, L.M., J. Biol. Chem. 235: 3603 (1960).Google Scholar
  7. 7.
    Kipnis, D. M., and Noall, M. W., Biochim. Biophys. Acta 28: 226 (1958).CrossRefGoogle Scholar
  8. 8.
    Christensen, H. N., and Oxender, D. L., Biochim. Biophys. Acta 78: 206 (1963).CrossRefGoogle Scholar
  9. 9.
    Berlinguet, L., Begin, N., and Babineau, L.M., Can. J. Biochem. Physiol 40: 1111 (1962).CrossRefGoogle Scholar
  10. 10.
    Christensen, H.N., and Clifford, J. B., J. Biol. Chem. 238: 1743 (1963).Google Scholar

Copyright information

© New England Nuclear Corporation 1965

Authors and Affiliations

  • Thomas R. Riggs
    • 1
  • Halvor N. Christensen
    • 1
  1. 1.Department of Biological ChemistryThe University of MichiganAnn ArborUSA

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