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Design and Analysis of Tracer Experiments—Biochemical Aspects

  • Martin D. Kamen

Abstract

The major successes which have attended the application of isotopic tracer techniques to biology have occurred at the biochemical level and have been concerned with elaborating the fate of relatively small molecules in biosynthesis. This is because of the availability of adequate procedures for purification and characterization of the relatively simple molecules concerned. These procedures include not only synthetic and degradative methods based on organic chemistry, but specific analytic characterization using enzymologic techniques. We may enumerate briefly a few outstanding examples.

Keywords

Aminolevulinic Acid Tracer Experiment Pyridine Nucleotide Product Citric Acid Tracer Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. (1).
    Wood, A.G. J. Biol. Chem. 194, 905 (1952).Google Scholar
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    Racker, E. and Krimsky, J. Fed. Proc. 17, 1135 (1958).Google Scholar
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    Kornberg, A., Lehman, I. R., Bessman, M. J., and Simms, E. S. Biochim. et Biophys. Acta 21, 197 (1956).Google Scholar

Copyright information

© New England Nuclear Corporation 1963

Authors and Affiliations

  • Martin D. Kamen
    • 1
  1. 1.Graduate Department of BiochemistryBrandeis UniversityWalthamUSA

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