Tritium Labeling by Other Methods
The labeling of compounds by techniques other than described by Dr. Wilzbach,† usually avoids the problem of radiation decomposition and frequently enables one to obtain considerably higher specific activities and specifically labeled positions. Thus, the tritium gas exposure method of labeling should be considered only after other synthetic routes have been eliminated or if a randomly labeled molecule is required.
KeywordsHigh Specific Activity Malonic Acid Lithium Aluminum Grignard Reagent Tritiated Water
- (4).Van Heyningen, Rittenberg, and Schoenheimer, J. Biol. Chem. 125, 495 (1938).Google Scholar