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Hemorheological Parameters in Some Vascular Diseases

  • J. F. Stoltz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 164)

Abstract

The origin of arterial diseases (acrosyndromes or peripheral vascular diseases is undoubtedly more generally attributed to parietal and vasomotor anomalies than to hemorheological disorders. However, in the light of recent investigations it would seem that increased erythrocyte aggregation is generally observed during arterial disease and is sometimes accompanied by reduced red cell deformability resulting in the appearance of a hyperviscosity syndrome. These rheological disturbances may have very significant bearing on the complications observed via three primary mechanisms: hemolysis (resulting in ADP release and promoting platelet aggregation), erythrocyte aggregation (resulting in a decreased blood flow (sludge)), and reduced erythrocyte deformability accompanied by reduced oxygen availability in the small blood vessels.

Keywords

Peripheral Arterial Disease Blood Viscosity Intermittent Claudication Plasma Viscosity Erythrocyte Aggregation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • J. F. Stoltz
    • 1
  1. 1.Hemorheology DepartmentRegional Blood Transfusion Centre BarboisVandoeuvre-lès-NancyFrance

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