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Platelet Function Changes in Acute Myocardial Infarction

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Thrombosis and Cardiovascular Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 164))

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Abstract

Whether the thrombotic component of myocardial infarction is primary or secondary in a given patient, platelet function alterations can influence many mechanisms — operating at the microenvi-ronmental level — from which it depends if the thrombotic lesion grows or sends platelet emboli to the smaller myocardial vessels.

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References

  1. S.C. Sharma, H.N. Setn, Platelet adhesiveness, plasma fibrinogen and fibrinolytic activity in acute myocardial infarction. Brit. Heart J. 40:526 (1978).

    Article  PubMed  CAS  Google Scholar 

  2. J. Gormsen, J.B. Knudsen, J.D. Nielsen, O. Amtorp, K. Skagen, Platelet function, coagulation, fibrinolysis, factor XIII and antithrombin III in acute transmural myocardial infarction. In: Proc. of Florence Int. Meet. on Myoc. Inf., May 8–12, 1979, p.233, Excerpta Medica, Amsterdam-Oxford-Princeton (1979).

    Google Scholar 

  3. P. Mehta, J. Mehta, Platelet function studies in coronary artery disease. V. Evidence for enhanced platelet micro-thrombus formation activity in acute myocardial infarction. Am. J. Cardiol. 43:757 (1979).

    Article  PubMed  CAS  Google Scholar 

  4. P. Steele, J. Rainwater, R. Vogel, Abnormal platelet survival time in men with myocardial infarction and normal coronary arteriogram. Am. J. Cardiol. 41:60 (1978).

    Article  PubMed  CAS  Google Scholar 

  5. K. Gjesdal, Platelet function and plasma free fatty acids during acute myocardial infarction and severe angina pectoris. Scand. J. Haematol. 17:205 (1976).

    Article  PubMed  CAS  Google Scholar 

  6. R.I. Handin, M. McDonough, M. Lesch, Evaluation of platelet factor four in acute myocardial infarction. Measurement by radioimmunoassay. J. Lab. Clin. Med. 91:340 (1978).

    PubMed  CAS  Google Scholar 

  7. H.H. Salem, J. Koutts, B.G. Firkin, Circulating platelet aggregates in ischaemic heart disease and their correlation to platelet life span. Thromb. Res. 17:707 (1980).

    Article  PubMed  CAS  Google Scholar 

  8. J. Zahavi, The role of platelets in myocardial infarction, ischemic heart disease, cerebrovascular disease, thromboembolic disorders and acute idiopathic pericarditis. Thromb. Haemostas. 38:1073 (1977).

    CAS  Google Scholar 

  9. M. Packham, Methods for detection of hypersensitive platelets. Thromb. Haemost. 40:175 (1978).

    PubMed  CAS  Google Scholar 

  10. V. Rasi, T. Torstila, E. Ikkala, Beta-thromboglobulin in acute myocardial infarction . Acta Med. Scand. (SuppL) 642:85 (1980).

    CAS  Google Scholar 

  11. A. Szczeklik, M. Serwonska, W. Lukasiewicz, J. Mruk, J. Musial, Arachidonate versus ADP-induced platelet aggregation in acute myocardial infarction. Thrombos.Haemostas. 42:822 (1979).

    CAS  Google Scholar 

  12. E. Granström, H. Kindhai, B. Samuelsson, Radioimmunoassay for thromboxane B2. Analyt. Letters 9;611 (1976).

    Article  Google Scholar 

  13. K.K. Wu, J.C. Hoak, Spontaneous platelet aggregation in arterial insufficiency: mechanisms and implications. Thrombos. Haemostas. 35:702 (1976).

    CAS  Google Scholar 

  14. P. Mehta, J. Mehta, Platelet function studies in coronary heart disease: VIII. Decreased platelet sensitivity to prostacyclin in patients with myocardial ischaemia. Thromb. Res. 18:273 (1980).

    Article  PubMed  CAS  Google Scholar 

  15. J.R. O’Brien, M.D. Etherington, R.D. Shuttleworth, Ticlopidine — an antiplatelet drug: effects in human volunteers. Thromb. Res. 13:245 (1978).

    Article  PubMed  Google Scholar 

  16. J. Valles, J. Aznar, M.T. Santos, Platelet fatty acids in acute myocardial infarction. Thromb. Res. 14:231 (1979).

    Article  PubMed  CAS  Google Scholar 

  17. E. Marcinkiewicz, L. Grodzinska, R.J. Gryglewski, Platelet aggregation and thromboxane A2 generation in platelet rich plasma. Pharmacol. Res. Commun. 10:1 (1978).

    Article  PubMed  CAS  Google Scholar 

  18. A. Szczeklik, R.J. Gryglewski, J. Musial, L. Grodzinska, M. Serwonska, E. Marcinkiewicz, Thromboxane generation and platelet aggregation in survivals of myocardial infarction. Thromb. Haemostas. 40:66 (1978).

    CAS  Google Scholar 

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© 1984 Plenum Press, New York

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Davì, G. et al. (1984). Platelet Function Changes in Acute Myocardial Infarction. In: Strano, A. (eds) Thrombosis and Cardiovascular Disease. Advances in Experimental Medicine and Biology, vol 164. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8616-2_17

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  • DOI: https://doi.org/10.1007/978-1-4684-8616-2_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8618-6

  • Online ISBN: 978-1-4684-8616-2

  • eBook Packages: Springer Book Archive

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