Risk Factors for Coronary Heart Disease and Platelet Functions

  • S. Renaud
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 164)


Epidemiologic studies have shown that a number of environmental factors or conditions are associated with coronary heart disease. Most of them are predisposing factors also known as risk factors. Other factors appear to have preventive effects. A list of these factors is reported in figure 1. Dietary saturated fats seem to have a key role since in their absence, as in Japanese in Japan, CHD does not occur whatever are the other risk factors (hypertension, diabetes, smoking) present in this population (1). Thus, saturated fats are considered as being the essential factor, while hypertension, diabetes, smoking, obesity, perhaps even oral contraceptives, might be regarded as predisposing factors. Finally, polyunsaturated fats, calcium and magnesium from the hard water (2) and alcohol (3), appear to be preventive factors.


Coronary Heart Disease Oral Contraceptive Platelet Function Ethinyl Estradiol Clotting Activity 


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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • S. Renaud
    • 1
  1. 1.Insera, Unit 63BronFrance

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