Transcription Termination and Its Control

  • Jeffrey W. Roberts


Transcription terminators form the natural boundaries of gene expression as well as act as sites of genetic regulation. E. coli and its phages have provided the central models to understand the biochemical mechanisms of these processes. The notable conservation of the two large major subunits of RNA polymerase between bacterial RNAP and all three eukaryotic enzymes,1 and the fact that termination is at least partly a function of these subunits,2 suggest that results from studies of E. coli should be of universal significance.


Phage Lambda Transcription Termination Pause Site Anti Termination Intrinsic Terminator 
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© R.G. Landes Company 1996

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  • Jeffrey W. Roberts

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