Regulation of Aerobic and Anaerobic Metabolism by the Arc system

  • A. Simon Lynch
  • Edmund C. C. Lin


During the course of the evolution of microbial bioenergetics, progenitors of E. coli probably acquired in a stepwise temporal fashion metabolic pathways for fermentation, anaerobic respiration, and aerobic respiration for the process of energy transduction.1,2 The acquisition of these different pathways, combined with the apparent development of successive layers of regulatory mechanisms to control them, enables E. coli to exploit adroitly environmental energy sources to their greatest possible advantage. To this end, a key strategy is to channel electrons from donors to terminal acceptors such that the overall potential difference is maximized for any given growth condition. Conspicuous consequences are improved growth rate and/or yield for any given carbon and energy source.


Escherichia Coli Anaerobic Metabolism Receiver Domain Phosphoryl Group Acetyl Phosphate 
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© R.G. Landes Company 1996

Authors and Affiliations

  • A. Simon Lynch
  • Edmund C. C. Lin

There are no affiliations available

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