History of the Pho System

  • Annamaria Torriani-Gorini


In Milan, I collaborated with the biochemist Luigi Gorini, with whom I subsequently shared my life. We were studying the resistance of E. coli to a new antibiotic “penicillin”1 and its effect on the metabolism of acidoproteolytic bacteria.2 In 1948 we went to Paris. I joined Jacques Monod at the Institut Pasteur on studies of regulation of carbon metabolism. Thus began my studies in the field of cellular regulatory processes, whose rules were being explored and characterized by André Lwoff, Max Delbrück, Herman Kalckar, Jacques Monod, Mike Doudoroff, Luigi Gorini, and Sol Spiegelman.


Nonsense Suppression Specific Transport System phoA Promoter Phosphate Transport System Alkaline Phosphatase Synthesis 
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© R.G. Landes Company 1996

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  • Annamaria Torriani-Gorini

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