A Comparative NMR Study
The nuclear magnetic resonance positions of the C-18 and C-19 methyl group protons in a series of A- and D-ring substituted steroidal androstane derivatives were measured and found to be in excellent agreement with the values calculated using Zurcher’s tables. In the A -ring hydroxylated derivatives the magnitude of the coupling between the proton on the carbon bearing the hydroxyl group and the protons on the adjacent carbon atoms was also found to be consistent with the proposed structures.
KeywordsNuclear Magnetic Resonance Methyl Group Proton Secondary Alcohol Deuterated Chloroform Methyl groupS
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