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Crystallization of Membrane Proteins

  • Hartmut Michel
Part of the NATO ASI Series book series (NSSA, volume 168)

Abstract

Prerequisite to understand the function and mechanism of action of any biological macromolecule is the knowledge of its structure. The only way to obtain detailed structural knowlege of large molecules is X-ray crystallography. Of course, X-ray crystallography needs crystals and the main area, where no crystals had been obtained until recently was the area of the membrane proteins.

Keywords

Membrane Protein Mixed Micelle Polar Interaction Critical Micellar Concentration Propane Sulfonate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    H. Michel (1983) Crystallization of Membrane Proteins Trends Biochem. Sci. 8, 56–59Google Scholar
  2. 2.
    R. M. Garavito, Z. Markovic-Housley and J. A. Jenkins (1986) The Growth and Characterization of Membrane Protein Crystals Journal of Crystal Growth 76, 701–709Google Scholar
  3. 3.
    R. C. Ford, D. Picot and R. M. Garavito (1987) Crystallization of the Photosystem I Reaction Centre EMBO J. 6, 1581–1586Google Scholar
  4. 4.
    S. Yoshikawa, T. Tera, Y. Takahashi, T. Tsukihara and W. S. Caughey (1988) Crystalline Cytochrome c Oxidase of Bovine Heart Mitochondrial Membrane: Composition and X-ray Diffraction Studies Proc. Natl. Acad. Sci. USA 85, 1354–1358CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Hartmut Michel
    • 1
  1. 1.Max-Planck-Institut für BiophysikAbteilung Molekulare MembranbiologieFrankfurt/M 71West Germany

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