Determination of Uric Acid in Serum: Comparison of a Standard Enzymatic Method and Isotachophoresis

  • F. Oerlemans
  • Th. Verheggen
  • F. Mikkers
  • F. Everaerts
  • C. de Bruyn
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)


Analytical techniques such a high-performance liquid chromatography (HPLC) and isotachophoresis can be applied for determination in biological fluids of a series of metabolites, including uric acid. Methods using HPLC have been reported for serum uric acid (1), blood and urine (2). Isotachophoresis has been employed in the analysis of nucleotides in muscle extracts (3) and urinary purines and pyrimidines, including uric acid (4).


Uric Acid Serum Uric Acid Effective Mobility Pyrimidine Nucleoside Homogentisic Acid 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • F. Oerlemans
    • 1
  • Th. Verheggen
    • 2
  • F. Mikkers
    • 2
  • F. Everaerts
    • 2
  • C. de Bruyn
    • 1
  1. 1.Department of Human Genetics, Faculty of MedicineUniversity of NijmegenNijmegenThe Netherlands
  2. 2.Department of Instrumental AnalysisEindhoven University of TechnologyEindhovenThe Netherlands

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