Effect of Allopurinol on Pyrimidine Metabolism in Human White Blood Cells. Role of the Salvage Pathway
The administration of allopurinol leads to an increase of urinary excretion of orotic acid and orotidine (Fox et al. 197o) due to an inhibition of orotidine-5-phosphate decarboxylase (ODC).
KeywordsSerum Uric Acid Salvage Pathway Orotic Acid Pyrimidine Metabolism Pyrimidine Synthesis
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