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Effect of Allopurinol on Pyrimidine Metabolism in Human White Blood Cells. Role of the Salvage Pathway

  • P. Banholzer
  • W. Gröbner
  • N. Zöllner
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)

Abstract

The administration of allopurinol leads to an increase of urinary excretion of orotic acid and orotidine (Fox et al. 197o) due to an inhibition of orotidine-5-phosphate decarboxylase (ODC).

Keywords

Serum Uric Acid Salvage Pathway Orotic Acid Pyrimidine Metabolism Pyrimidine Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • P. Banholzer
    • 1
  • W. Gröbner
    • 1
  • N. Zöllner
    • 1
  1. 1.Medical PoliclinicUniversity of MunichMunichDeutschland

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