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Xanthine Oxidase Activity in Human Intestines. Histochemical and Radiochemical Study

  • C. Auscher
  • N. Amory
  • P. van der Kemp
  • F. Delbarre
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)

Abstract

Xanthine oxidase (xanthine oxygen-oxidoreductase EC 1.2.3.2.) catalyses oxidation of hypoxanthine and xanthine to uric acid. In man, small intestines and liver are the only tissues that normally show abundant xanthine oxidase (XO) activity. But localization, level, form of catalytic activity and physiological function in the different tissues are not clearly known. In xanthinuria, characterized by a gross deficiency of XO in the tissues it is not known whether the variations in the level of residual activity of XO represent methodologic limitations or heterogeneity of the genetic and molecular defect.

Keywords

Uric Acid Xanthine Oxidase Human Intestine Xanthine Oxidase Activity Histochemical Localization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • C. Auscher
    • 1
  • N. Amory
    • 1
  • P. van der Kemp
    • 1
  • F. Delbarre
    • 1
  1. 1.Institut de RhumatologieUnité no 5 INSERM - ERA 337 CNRS, Hôpital CochinParisFrance

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