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Xanthine Oxidase Activity in Human Intestines. Histochemical and Radiochemical Study

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Purine Metabolism in Man—III

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 122B))

Abstract

Xanthine oxidase (xanthine oxygen-oxidoreductase EC 1.2.3.2.) catalyses oxidation of hypoxanthine and xanthine to uric acid. In man, small intestines and liver are the only tissues that normally show abundant xanthine oxidase (XO) activity. But localization, level, form of catalytic activity and physiological function in the different tissues are not clearly known. In xanthinuria, characterized by a gross deficiency of XO in the tissues it is not known whether the variations in the level of residual activity of XO represent methodologic limitations or heterogeneity of the genetic and molecular defect.

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References

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Authors and Affiliations

  1. Institut de Rhumatologie, Unité no 5 INSERM - ERA 337 CNRS, Hôpital Cochin, Paris, France

    C. Auscher, N. Amory, P. van der Kemp & F. Delbarre

Authors
  1. C. Auscher
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  2. N. Amory
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  3. P. van der Kemp
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  4. F. Delbarre
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Editor information

Editors and Affiliations

  1. Fundación Jiménez Díaz, Madrid, Spain

    Aurelio Rapado

  2. M.R.C. Clinical Research Centre, Harrow, England

    R. W. E. Watts

  3. Department of Human Genetics, University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands

    Chris H. M. M. De Bruyn

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© 1980 Plenum Press, New York

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Auscher, C., Amory, N., van der Kemp, P., Delbarre, F. (1980). Xanthine Oxidase Activity in Human Intestines. Histochemical and Radiochemical Study. In: Rapado, A., Watts, R.W.E., De Bruyn, C.H.M.M. (eds) Purine Metabolism in Man—III. Advances in Experimental Medicine and Biology, vol 122B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8559-2_33

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  • DOI: https://doi.org/10.1007/978-1-4684-8559-2_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8561-5

  • Online ISBN: 978-1-4684-8559-2

  • eBook Packages: Springer Book Archive

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