Advertisement

Nicotinamide and Liver Xanthine Oxdidase

  • A. Di Stefano
  • M. Pizzichini
  • E. Marinello
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)

Abstract

When rats receive injection of high doses of nicotinamide, there is a temporary 10 fold increase in the diphosphyridine nucleotide content of the liver (1).

Keywords

Nicotinic Acid Xanthine Oxidase Xanthine Oxidase Activity Riboflavin Deficiency Wister Strain Male 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    A. Bonsignore and C. Ricci, Sulla natura del cemposto dosabile come N1 — metilnicotinamide nel fegato di ratti trattati con nicotinamide. Identificazione con il DPN. Boll. Soc. It. Biol. Sper. 25:710 (1949).Google Scholar
  2. 2.
    L. Shuster, T.A. Langan, Jr W.O. Kaplan, A. Goldin, Significance of induced in vivo synthesis of diphosphate pyridine Nature 182:512 (1958).PubMedCrossRefGoogle Scholar
  3. 3.
    A. Di Stefano, M. Pizzichini and E. Marinello, Incorporazione di glicina — U — 14C nell’allantoina urinaria del ratto trattato con nicotinamide. Boll. Soc. It. Biol. Chem. LIV:425 (1978).Google Scholar
  4. 4.
    L. Shuster and A. Goldin, The effect of nicotinamide on incorporation in vivo of formate 14C. J. Biol. Chem. 230:878 (1958).Google Scholar
  5. 5.
    A. Mangoni, V. Pennetti and M.A. Spadoni, Aumento adattativo di xantina ossidasi in topini alimentati con dieta con diverso contenuto proteico. Boll. Soc. Biol. Sper. 31:1397 (1355).Google Scholar
  6. 6.
    E. Della Corte and F. Stirpe, Regulation of xanthine dehydrogenase in chick liver. Biochem. J. 102:520 (1967).Google Scholar
  7. 7.
    R. Marcolongo, E. Marinello, G. Pcmpucci and R. Pagani, The role of xanthine oxidase in hyperuricemic states. Arthritis and Rheumatism 17:430 (1974).PubMedCrossRefGoogle Scholar
  8. 8.
    F. Stirpe and E. Della Corte, The regulation of rat liver xanthine oxidase. J. Biol. Chem. 244:3855 (1969).PubMedGoogle Scholar
  9. 9.
    E. Della Corte and F. Stirpe, Regulation of rat liver xanthine oxidase. Biochem. J. 108:349 (1968).Google Scholar
  10. 10.
    E. Della Corte and F. Stirpe, The regulation of rat liver xanthine oxidase. Biochem. J. 126:739 (1972).Google Scholar
  11. 11.
    H.B. Burch, O.H. Lcwry, A.M. Padilla and A.M. Cotibs, Effects of riboflavin deficiency and realimentation on flavin enzyme of tissues. J. Biol. Chem. 233:29 (1956).Google Scholar
  12. 12.
    R. Fried and L. W. Fried, in H.U. Bergmeyer Methodem der enzy-matischen Analyse Verlag Chemie, Weinheim (1970).Google Scholar
  13. 13.
    C. Ricci, Regolazione ormonale della biosintesi epatica del ni-cotinamide-adenina-nucleotide, relazione tenuta al XIV conve-gno della salute, Ferrara (27–28 maggio 1967).Google Scholar
  14. 14.
    A. Di Stefano, M. Pizzichini and E. Marinello, Regolazione della xantina ossidasi epatica. Atti del congresso S.I.B., ccmunicazione VII:16 (1978).Google Scholar
  15. 15.
    P.B. Rcwe and J.B. Wyngaarden, The mechanism of djetary alteration in rat hepatic xanthine oxidase leve].. J. Biol. Chem. 241:5571 (1976).Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • A. Di Stefano
    • 1
  • M. Pizzichini
    • 1
  • E. Marinello
    • 2
  1. 1.Dept. Biological ChemistryUniversity SienaItaly
  2. 2.Dept. Biological ChemistryE.U.L.O. BresciaItaly

Personalised recommendations