Purine Metabolism in Rat Skeletal Muscle

  • E. R. Tully
  • T. G. Sheehan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)


About 40 to 50% of man’s weight is contributed by skeletal muscle,1. Muscle is a highly differentiated tissue, and as such is metabolically less complex than many other tissues. It has a contractile function in which ATP plays a major role. At rest there is a steady loss of some purines from muscle,2, while during exercise release of inosine and hypoxanthine in particular, increases markedly,3. A mechanism or mechanisms must exist to replace the purine lost from the tissue.


Adenine Nucleotide Adenosine Deaminase Incorporation Rate Purine Metabolism Purine Nucleotide 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • E. R. Tully
    • 1
  • T. G. Sheehan
    • 1
  1. 1.Department of BiochemistryUniversity CollegeCorkIreland

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